By Arthur M. Silverstein
It is a professional-level highbrow historical past of the improvement of immunology from approximately 1720 to approximately 1970. starting with the paintings and insights of the early immunologists within the 18th century, Silverstein lines the advance of the most important rules that have shaped immunology right down to the maturation of the self-discipline within the decade following the second one global battle. Emphasis is put on the philosophic and sociologic weather of the medical milieu within which immunology has constructed, supplying a historical past to the huge tradition of the self-discipline.
* A professional-level highbrow background of the advance of immunology from approximately 1720 to 1970, with emphasis put on the social weather of the medical milieu during which glossy immunology evolved
* Written by way of an writer rather well identified either as a historian of scientific technological know-how and for his huge examine contributions to the immunopathology of the eye
* the one entire heritage of immunology to be had
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As Eggs of different Fowls are from one another; therefore every sort of these Ovula can produce only its own proper Foetus . . and therefore the Pestilence can never breed the Small Pox, nor the Small Pox the Measles . . All Men have in them those specific Sorts of Ovula which bring forth Small Pox and Measles, and therefore we say that all Men are liable to them . . The Ovula always lie quiet and unprolific, till impregnated, and therefore these Distempers seldom come without Infection, which is as it were the Male, and the active Cause.
I have concluded this review of theories of acquired immunity just short of those "modern" concepts that guide investigators today. In Theories of Acquired Immunity 21 contrast to the theories described in this chapter in which the infected host was generally portrayed as a passive receptable in which disease ran its course and immunity might be established, current theories involving antibodies, complement, macrophages, and lymphocytes speak of hostparasite interactions to which the infected or immunized individual makes an active contribution.
Leipzig und Bautzen) 17, 206 (1723). 20. H. , given to Mr. Randy to be published, Anno 1736. D. S. Philos. Trans. R. Soc, London 49, 516 (1756). 21. Weekly J. or Br. Gazetteer J u n e 17, p. 1952 (1721); Applebee's Orig. Weekly J. J u n e 17, p. 2087 (1721). 22. Hardwicke papers, Vol. 786, Add. MS. 36, 134, f. 58, British Museum, London. 23. Hardwicke papers, ref. 22. 24. Applebee's Orig. Weekly J. Aug. 12, p. 2134 (1721); Weekly J. or Br. Gazetter Aug. 12, p. 1999 (1721); Weekly J. or Saturdafs-Post Aug.